Michael Fenech Selected Research

Genomic Instability

9/2018	Role of PON1, SOD2, OGG1, XRCC1, and XRCC4 polymorphisms on modulation of DNA damage in workers occupationally exposed to pesticides.
1/2018	Chronic occupational exposure endured by tobacco farmers from Brazil and association with DNA damage.
1/2017	Whey protein isolate improves vitamin B12 and folate status in elderly Australians with subclinical deficiency of vitamin B12.
10/2016	Role of Sirtuins in Maintenance of Genomic Stability: Relevance to Cancer and Healthy Aging.
6/2016	The Role of Genetic Polymorphisms as Related to One-Carbon Metabolism, Vitamin B6, and Gene-Nutrient Interactions in Maintaining Genomic Stability and Cell Viability in Chinese Breast Cancer Patients.
3/2016	Genotoxicity and cytotoxicity of chromium, copper, manganese and lead, and their mixture in WIL2-NS human B lymphoblastoid cells is enhanced by folate depletion.
10/2015	Potential role of folate in pre-eclampsia.
10/2015	Chromosomal DNA damage in APOE ɛ4 carriers and noncarriers does not appear to be different.
6/2015	Genome instability biomarkers and blood micronutrient risk profiles associated with mild cognitive impairment and Alzheimer's disease.
6/2015	Zinc supplementation influences genomic stability biomarkers, antioxidant activity, and zinc transporter genes in an elderly Australian population with low zinc status.

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Michael Fenech Research Topics

Disease

35	Neoplasms (Cancer) 01/2022 - 11/2002
33	Genomic Instability 09/2018 - 07/2002
17	Chromosome Breakage 10/2016 - 03/2003
15	Chromosomal Instability (Chromosome Stability) 10/2021 - 11/2002
10	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 11/2007
8	Necrosis 11/2020 - 10/2003
7	Breast Neoplasms (Breast Cancer) 09/2021 - 07/2004
7	Chromosome Aberrations (Chromosome Abnormalities) 07/2021 - 12/2002
7	Inflammation (Inflammations) 01/2021 - 01/2006
7	Cognitive Dysfunction 01/2018 - 01/2012
6	Folic Acid Deficiency (Folic Acid Deficiencies) 01/2022 - 01/2004
5	Dementia (Dementias) 01/2020 - 08/2014
4	Bites and Stings (Sting) 07/2021 - 10/2020
4	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 12/2007
4	Aneuploidy (Aneuploid) 10/2020 - 07/2004
4	Malnutrition (Nutritional Deficiencies) 10/2016 - 06/2003
4	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2015 - 01/2009
4	Carcinogenesis 07/2013 - 06/2009
3	Chronic Disease (Chronic Diseases) 07/2021 - 09/2014
3	Lung Neoplasms (Lung Cancer) 01/2011 - 05/2008
2	Type 2 Diabetes Mellitus (MODY) 01/2022 - 10/2021
2	Hematologic Neoplasms (Hematological Malignancy) 08/2021 - 02/2015
2	Infections 07/2021 - 09/2014
2	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 12/2018
2	Cardiovascular Diseases (Cardiovascular Disease) 03/2016 - 01/2011
2	Pre-Eclampsia (Preeclampsia) 10/2015 - 04/2013
2	Down Syndrome (Down's Syndrome) 07/2015 - 02/2008
2	Iron Deficiencies 05/2012 - 01/2009
2	Autistic Disorder (Autism) 04/2012 - 06/2010
2	Infertility (Sterility) 01/2011 - 06/2003
2	Weight Loss (Weight Reduction) 12/2010 - 06/2009
2	Pain (Aches) 07/2010 - 01/2006
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 08/2021
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 08/2021
1	Noncommunicable Diseases 07/2021
1	RNA Virus Infections 07/2021
1	Hyperglycemia 01/2021

Drug/Important Bio-Agent (IBA)

51	Biomarkers (Surrogate Marker)IBA 01/2022 - 07/2002
26	Folic Acid (Vitamin M)FDA LinkGeneric 03/2016 - 11/2002
22	DNA (Deoxyribonucleic Acid)IBA 07/2021 - 12/2002
8	MutagensIBA 10/2016 - 06/2003
7	HomocysteineIBA 01/2018 - 01/2004
7	MicronutrientsIBA 06/2015 - 11/2002
6	4-nitrophenethyl bromide (NPB)IBA 01/2017 - 03/2003
5	Biological ProductsIBA 01/2021 - 05/2011
5	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 01/2017 - 07/2010
5	Methionine (L-Methionine)FDA Link 10/2015 - 01/2003
5	ZincIBA 06/2015 - 05/2005
5	AntioxidantsIBA 06/2015 - 01/2006
5	Proteins (Proteins, Gene)FDA Link 12/2010 - 12/2007
4	Vitamin D FDA LinkGeneric 01/2021 - 05/2012
4	ChromatinIBA 10/2020 - 02/2008
4	CarcinogensIBA 10/2016 - 12/2002
4	UracilIBA 05/2012 - 07/2004
3	Apolipoproteins E (ApoE)IBA 01/2020 - 08/2014
3	Vitamin B Complex (B Vitamins)IBA 01/2018 - 10/2015
3	VitaminsIBA 11/2017 - 05/2005
3	CarbonIBA 11/2017 - 10/2015
3	CalciumIBA 10/2015 - 05/2005
3	Amyloid beta-PeptidesIBA 01/2014 - 01/2007
3	IronIBA 05/2012 - 01/2009
3	Riboflavin (Vitamin B2)FDA LinkGeneric 01/2010 - 01/2004
2	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 11/2017
2	Pyruvaldehyde (Methylglyoxal)IBA 01/2022 - 10/2021
2	InterferonsIBA 07/2021 - 10/2020
2	cyclic guanosine monophosphate-adenosine monophosphateIBA 07/2021 - 10/2020
2	CytokinesIBA 07/2021 - 10/2015
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 04/2010
2	XenobioticsIBA 09/2018 - 01/2018
2	tau Proteins (tau Protein)IBA 11/2017 - 01/2007
2	LipidsIBA 11/2017 - 08/2014
2	EnzymesIBA 06/2016 - 10/2015
2	Hormones (Hormone)IBA 06/2016 - 01/2015
2	Vitamin B 6IBA 06/2016 - 04/2013
2	polaprezinc (Z 103)IBA 06/2015 - 02/2011
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 08/2014 - 01/2013
2	Fatty Acids (Saturated Fatty Acids)IBA 08/2014 - 04/2014
2	Cytostatic AgentsIBA 01/2014 - 04/2012
2	Telomerase (Telomerase Reverse Transcriptase)IBA 06/2013 - 05/2012
2	Choline (Choline Chloride)IBA 04/2012 - 01/2003
2	CarbohydratesIBA 12/2010 - 05/2009
2	PolyphenolsIBA 02/2009 - 01/2009
2	Grape Seed ExtractIBA 02/2009 - 01/2009
2	Molecular Probes (Molecular Probe)IBA 01/2008 - 01/2005
2	Thymidine Monophosphate (TMP)IBA 01/2008 - 07/2004
2	Biotin (Vitamin H)FDA Link 05/2005 - 07/2004
1	LeptinIBA 09/2021
1	Dietary Fiber FDA Link 09/2021
1	AdipokinesIBA 09/2021
1	AdiponectinIBA 09/2021
1	navitoclaxIBA 08/2021
1	Decitabine FDA Link 08/2021
1	A-Form DNA (A-DNA)IBA 08/2021
1	7,14-dihydroxypregn-4-ene-3,20-dioneIBA 07/2021
1	RNA (Ribonucleic Acid)IBA 07/2021
1	immune RNA (I-RNA)IBA 07/2021

Therapy/Procedure

5	Therapeutics 01/2022 - 06/2015
4	Radiotherapy 01/2017 - 06/2011
2	Reducing Diet 12/2010 - 05/2009
1	Precision Medicine 07/2021